The history of Central Mississippi Health Services, Inc. (CMHS) is closely linked to MS Family Health Center (MFHC), as their missions have always been similar. The missions of the clinics were similar in the sense that Dr. Robert Smith, who was a principal founder of Community Health Centers locally and nationally, opened MFHC in 1963 on Lynch Street near Jackson State University. In 1969, the Winter Street clinic was opened.In 1995, all assets and property of MFHC was donated by Dr. Robert Smith to CMHS. A Board of Directors was formed of local leaders and users of the clinic, and Dr. Robert Smith became the Chief Executive Officer.
In 1995, MFHC evolved into CMHS and became the first Federally Qualified Health Center (FQHC) look-a-like in the state of Mississippi. In 2003, the organization was funded and became a full FQHC. CMHS soon expanded and opened two satellite clinics: Tougaloo, the medical clinic on the campus of Tougaloo College within the Owens Health and Wellness Center, provides medical care to students, faculty, and the community; and the Robinson Road Extension clinic, which includes primary care and OB-GYN services. These clinics employ doctors, nurse practitioners, and support staff.